Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | PTGES | O14684 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MYOC | Q99972 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155742 | 0.86 | ATM (0.69) | BAZ1AMEN1KMT2AMAPTNPC1 | |
| SCHEMBL6302157 | 0.86 | MEN1 (1.00) | MEN1KMT2APTGESMAPTNPC1 | |
| SCHEMBL1177730 | 0.86 | MEN1 (1.00) | MEN1KMT2APTGESMAPTNPC1 | |
| SCHEMBL5448340 | 0.86 | ALDH1A1 (0.67) | BAZ1AMEN1KMT2APTGESMAPT | |
| SCHEMBL10779335 | 0.86 | BAZ1A (0.76) | BAZ1AMEN1KMT2APTGESMAPT | |
| SCHEMBL29663991 | 0.84 | RAB9A (0.76) | BAZ1AMEN1KMT2AMAPTNPC1 | |
| SCHEMBL4402970 | 0.84 | CNR1 (0.72) | BAZ1AMEN1KMT2APTGESMAPT | |
| SCHEMBL11726706 | 0.83 | RAB9A (0.68) | BAZ1AMEN1KMT2APTGESMAPT | |
| SCHEMBL7158133 | 0.83 | MAPT (0.64) | BAZ1AMEN1KMT2APTGESMAPT | |
| SCHEMBL218018 | 0.82 | MAPT (0.78) | BAZ1AMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |