Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057929 | 0.87 | PDE3B (0.60) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL6740939 | 0.79 | KDM1A (0.51) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL5068409 | 0.77 | MAPT (1.00) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21799330 | 0.76 | MAPT (0.97) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL7314031 | 0.76 | MAPT (1.00) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL23558362 | 0.74 | MAPT (0.51) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL4596554 | 0.73 | KIF11 (0.68) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL8525270 | 0.73 | SMN1; SMN2 (0.70) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6202875 | 0.72 | MAPT (0.64) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Bromide SCHEMBL6201510 | 0.72 | MAPT (0.64) | MAPTALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62048679-A | — | — | None | — | — | JP | disclosed |
| JP-S6248679-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1987-03-03 | — | — | JP | disclosed |