Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26068495 | 0.84 | ALDH1A1 (0.38) | NAAATSHRALDH1A1HCAR2LMNA | |
| SCHEMBL14569636 | 0.82 | NAAA (0.53) | NAAATSHREPHX1ALDH1A1CES2 | |
| SCHEMBL27418312 | 0.82 | NAAA (0.53) | NAAATSHREPHX1ALDH1A1CES2 | |
| SCHEMBL28143253 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1CES2 | |
| SCHEMBL4254663 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1HCAR2 | |
| SCHEMBL18252664 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1HCAR2 | |
| SCHEMBL27714510 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1CES2 | |
| SCHEMBL1456675 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1HCAR2 | |
| SCHEMBL26686917 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1CES2 | |
| SCHEMBL10895854 | 0.82 | NAAA (0.57) | NAAATSHREPHX1ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642290-A | OXIDOREDUCTASE ENZYMES FERMENTING 4-SUBSTITUTED-ACETOACETIC ESTERS OR AMIDES | SIH CHARLES J (US) | 1987-02-10 | — | — | US | claimed |