SCHEMBL4254663

SCHEMBL4254663

CCCCCCOC(=O)C(Cl)C(Cl)C(=O)OCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.57
EPHX1 P07099 1/20 0.53
TSHR P16473 3/20 0.52
HCAR2 Q8TDS4 1/20 0.48
RAD52 P43351 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ALDH1A1 P00352 2/20 0.47
FAAH O00519 1/20 0.47
LMNA P02545 1/20 0.47
ACHE P22303 6/20 0.47
DGKA P23743 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4250591 0.98 NAAA (0.54) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL2861335 0.91 ALDH1A1 (0.56) NAAAEPHX1TSHRHCAR2ALDH1A1
SCHEMBL28096325 0.88 NAAA (0.50) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL18252664 0.87 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL1456675 0.87 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL11783332 0.85 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL21381336 0.85 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL15820666 0.85 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL21811909 0.85 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL21811448 0.85 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NAAA 416/4885EPHX1 1076/4885TSHR 1710/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NAAA 416/4885EPHX1 1076/4885TSHR 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.