Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.62 |
| ▸ | ACE | P12821 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 9/20 | 0.57 |
| ▸ | MMP1 | P03956 | 4/20 | 0.57 |
| ▸ | MMP3 | P08254 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780422 | 0.85 | MME (0.63) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL8466382 | 0.85 | MMP2 (0.67) | MMP2MMP1MMP3 | |
| SCHEMBL28211408 | 0.83 | MMP2 (0.57) | MMP2MMP1MMP3 | |
| SCHEMBL5017227 | 0.83 | MMP2 (0.57) | MMP2MMP1MMP3 | |
| SCHEMBL10447979 | 0.82 | MME (0.81) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL5258058 | 0.82 | FAAH (0.57) | ALDH1A1MAPTMMP2MMP1MMP3 | |
| SCHEMBL19437143 | 0.81 | MME (0.70) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10957172 | 0.81 | FOLH1 (0.66) | MMP2MMP1MMP3 | |
| SCHEMBL3242850 | 0.81 | FOLH1 (0.66) | MMP2MMP1MMP3 | |
| SCHEMBL9653477 | 0.81 | FOLH1 (0.66) | MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |