SCHEMBL10780992

SCHEMBL10780992

NC(=O)OC(=O)c1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.59
KDM4E B2RXH2 7/20 0.59
ALDH1A1 P00352 5/20 0.59
HSD17B10 Q99714 5/20 0.59
TSHR P16473 2/20 0.59
MAPT P10636 2/20 0.59
LMNA P02545 2/20 0.59
ALOX15 P16050 1/20 0.55
TDP1 Q9NUW8 2/20 0.53
CA1 P00915 2/20 0.50
CA9 Q16790 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 1/20 0.50
CA2 P00918 1/20 0.50
HMGB1 P09429 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA7 P43166 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CA14 Q9ULX7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29525350 0.87 LMNA (0.68) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL3908136 0.87 LMNA (0.68) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL8439409 0.87 TSHR (0.46) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL6207827 0.81 HPGD (0.52) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL1491974 0.81 HPGD (0.62) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL28061876 0.81 ALDH1A1 (0.50) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL28182666 0.81 LIG1 (0.54) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL28262620 0.80 ALDH1A1 (0.58) HPGDKDM4EALDH1A1HSD17B10TSHR
Salicylamide SCHEMBL28072629 0.80 HPGD (0.66) HPGDKDM4EALDH1A1HSD17B10TSHR
SCHEMBL9950596 0.79 ALDH1A1 (0.62) HPGDKDM4EALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0090510-B1 O-CARBAMOYL SALICYLATES AND THEIR PREPARATION Council of Scientific and Industrial Research (IN) 1987-11-11 EP claimed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP claimed
CN-115260116-B Preparation method of 8- (2-hydroxybenzoamido) sodium octoate and benzoxazine-2, 4-diketone and 8-bromooctoate 株洲壹诺生物技术有限公司 2024-04-12 CN disclosed
EP-0090510-B1 O-CARBAMOYL SALICYLATES AND THEIR PREPARATION Council of Scientific and Industrial Research (IN) 1987-11-11 EP disclosed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP disclosed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP disclosed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP disclosed