Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339716 | 0.82 | LMNA (0.56) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL31424058 | 0.82 | LMNA (0.56) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL9561863 | 0.81 | LMNA (0.59) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL10780992 | 0.81 | HPGD (0.59) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL6207031 | 0.81 | CES2 (0.47) | HPGDALDH1A1MAPTLMNAALOX15 | |
| SCHEMBL6205116 | 0.81 | NPC1 (0.50) | HPGDALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6206781 | 0.81 | RAB9A (0.50) | HPGDALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL3908136 | 0.80 | LMNA (0.68) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL29525350 | 0.80 | LMNA (0.68) | HPGDALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL6208809 | 0.78 | HPGD (0.51) | HPGDALDH1A1HSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |