Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750099 | 0.81 | CYP2C19 (0.47) | TSHRCNR2ALDH1A1 | |
| SCHEMBL10781391 | 0.77 | CHRM2 (0.45) | KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL11106441 | 0.75 | CNR2 (0.46) | L3MBTL1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL6136683 | 0.72 | MAPT (0.42) | MAPTCRHBPCRHR2L3MBTL1CYP1A2 | |
| SCHEMBL29337376 | 0.72 | NR1H2 (0.57) | MAPTCRHBPCRHR2KCNH2ALDH1A1 | |
| SCHEMBL6607407 | 0.71 | MAPT (0.58) | MAPTCRHBPCRHR2L3MBTL1CYP1A2 | |
| SCHEMBL9392854 | 0.71 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29334037 | 0.70 | MAPT (0.53) | MAPTCRHBPCRHR2L3MBTL1MAPK1 | |
| SCHEMBL3737073 | 0.70 | KCNJ1 (0.51) | MAPTCRHBPCRHR2MAPK1KCNH2 | |
| SCHEMBL2166937 | 0.69 | MAPT (0.40) | MAPTCRHBPCRHR2L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115198-B1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTIVE ELEMENTS | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4539282-A | SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0115198-A1 | Electrophotographic photoconductive elements | TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |