Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297471 | 0.85 | L3MBTL1 (0.40) | MAPTMGLLLMNAMEN1KMT2A | |
| SCHEMBL2166937 | 0.80 | MAPT (0.40) | MAPTMGLLLMNAMEN1KMT2A | |
| SCHEMBL10608761 | 0.75 | MAPT (0.49) | MAPTMGLLLMNAPOLBALDH1A1 | |
| SCHEMBL6680576 | 0.75 | MAPT (0.49) | MAPTMGLLLMNAMEN1KMT2A | |
| SCHEMBL9392854 | 0.75 | ALDH1A1 (0.62) | MAPTMGLLLMNAMEN1KMT2A | |
| SCHEMBL8667678 | 0.74 | MAPT (0.47) | MAPTMGLLLMNAPOLBALDH1A1 | |
| SCHEMBL28807512 | 0.74 | MAPT (0.47) | MAPTMGLLLMNAMEN1KMT2A | |
| SCHEMBL28488450 | 0.74 | MAPT (0.47) | MAPTMGLLLMNAPOLBALDH1A1 | |
| SCHEMBL8727031 | 0.74 | MGLL (0.46) | MAPTMGLLMEN1KMT2AALDH1A1 | |
| SCHEMBL9165350 | 0.74 | MGLL (0.46) | MAPTMGLLMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081140-B1 | Novel Pyrimidine-2,4,6-trione compounds | DSM IP ASSETS BV (NL) | 2005-06-01 | — | — | EP | disclosed |
| US-6573269-B1 | Compounds for protecting surface of substrate from ultraviolet light | ROCHE VITAMINS INC. | 2003-06-03 | — | — | US | disclosed |
| EP-1081140-A2 | Novel Pyrimidine-2,4,6-trione compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2001-03-07 | — | — | EP | disclosed |