Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784612 | 0.81 | POLB (0.33) | KDM4E | |
| SCHEMBL11318486 | 0.79 | KDM4E (0.35) | KDM4EMAPTHTT | |
| SCHEMBL11312372 | 0.79 | MAPT (0.34) | KDM4EHSP90AA1HSP90AB1MAPTALDH1A1 | |
| SCHEMBL11315221 | 0.77 | CYP3A4 (0.32) | MAPK1SMN1; SMN2 | |
| SCHEMBL11795132 | 0.76 | MAPT (0.40) | KDM4EHSP90AA1MAPTHTTALDH1A1 | |
| SCHEMBL11092708 | 0.73 | LMNA (0.30) | MAPT | |
| Acetic Acid SCHEMBL11810691 | 0.73 | MAPT (0.36) | KDM4EMAPTHTT | |
| SCHEMBL11084435 | 0.71 | HTT (0.35) | HTTALDH1A1 | |
| SCHEMBL11309175 | 0.71 | GAA (0.36) | MAPTALDH1A1 | |
| SCHEMBL11406725 | 0.71 | HSP90AA1 (0.31) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675130-A | HAIR DYES | L'OREAL (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4246181-A | HAIR DYE | L'OREAL (FR) | 1981-01-20 | — | — | US | disclosed |