Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312258 | 0.90 | MEN1 (0.36) | GAAMEN1RAB9AKMT2AMAPT | |
| SCHEMBL11312372 | 0.87 | MAPT (0.34) | GAAMEN1RAB9AKMT2AMAPT | |
| SCHEMBL11306613 | 0.83 | PABPC1 (0.43) | GAAMEN1RAB9AKMT2AMAPT | |
| SCHEMBL11312702 | 0.78 | MAPT (0.33) | MEN1RAB9AKMT2AMAPT | |
| SCHEMBL11308355 | 0.78 | MAPT (0.36) | GAAMEN1RAB9AKMT2AMAPT | |
| SCHEMBL13525232 | 0.78 | MAPT (0.37) | GAAMEN1RAB9AKMT2AMAPT | |
| SCHEMBL11404430 | 0.77 | LMNA (0.38) | MEN1RAB9AKMT2AMAPTALDH1A1 | |
| SCHEMBL11309157 | 0.75 | PABPC1 (0.44) | MEN1RAB9AKMT2AMAPTNPSR1 | |
| SCHEMBL11308330 | 0.73 | FSCN1 (0.31) | — | |
| SCHEMBL11321038 | 0.73 | PABPC1 (0.42) | GAAMEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |