Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23017662 | 0.85 | ERCC5 (0.49) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL7438839 | 0.84 | ERCC5 (0.57) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL11761251 | 0.82 | ERCC5 (0.58) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL10780319 | 0.81 | L3MBTL1 (0.53) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10481543 | 0.80 | ERCC5 (0.60) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL9588184 | 0.80 | MAPT (0.51) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL7429982 | 0.80 | ALDH1A1 (0.54) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL8858796 | 0.79 | ERCC5 (0.59) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL7690326 | 0.79 | ERCC5 (0.64) | ERCC5FEN1MEN1KMT2AALDH1A1 | |
| SCHEMBL20245335 | 0.79 | ERCC5 (0.51) | ERCC5FEN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4694005-A | CARDIOTONIC, HYPOTENSIVE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-15 | — | — | US | disclosed |