Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782158 | 0.84 | KMT2A (0.54) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| Methane SCHEMBL11375164 | 0.82 | KMT2A (0.53) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL941121 | 0.82 | JAK3 (0.48) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL9588184 | 0.81 | MAPT (0.51) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL6755940 | 0.81 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL11109230 | 0.81 | MAOA (0.52) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL25167892 | 0.81 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL23014182 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL1945591 | 0.80 | MTNR1A (0.59) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL10783237 | 0.80 | ERCC5 (0.54) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |