SCHEMBL10784137

SCHEMBL10784137

CCC(O)c1cc(C(O)CC)cc(C(O)CC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
PGR P06401 2/20 0.39
TSHR P16473 4/20 0.37
ADRB2 P07550 8/20 0.37
HIF1A Q16665 2/20 0.37
ADRA1A P35348 2/20 0.37
PDE2A O00408 1/20 0.36
CYP3A4 P08684 3/20 0.35
CYP2C9 P11712 2/20 0.35
CASP7 P55210 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
ESR1 P03372 1/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20868524 0.84 LMNA (0.50) LMNATSHRADRB2ADRA1APDE2A
SCHEMBL20868405 0.84 LMNA (0.50) LMNATSHRADRB2ADRA1APDE2A
SCHEMBL27549810 0.84 LMNA (0.50) LMNAPGRTSHRADRB2HIF1A
SCHEMBL17706596 0.84 ADRB2 (0.55) LMNATSHRADRB2HIF1AADRA1A
SCHEMBL11595350 0.84 LMNA (0.70) LMNATSHRADRB2HIF1AADRA1A
SCHEMBL2991074 0.84 ADRB2 (0.55) LMNATSHRADRB2HIF1AADRA1A
SCHEMBL14354811 0.83 LMNA (0.45) LMNAPGRTSHRADRB2HIF1A
SCHEMBL24664872 0.82 LMNA (0.48) LMNATSHRADRB2HIF1AADRA1A
SCHEMBL4651304 0.82 LMNA (0.48) LMNAADRB2ADRA1APDE2ACYP3A4
SCHEMBL2986684 0.82 HKDC1 (0.52) LMNATSHRADRB2HIF1AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714767-B1 PHOTOCHROMIC POLYMERS VIVIMED LABS EUROPE LTD (GB) 2020-07-22 EP disclosed
US-10545405-B2 Actinic ray-sensitive or radiation-sensitive resin composition, actinic ray-sensitive or radiation-sensitive film, mask blank including actinic ray-sensitive or radiation-sensitive film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2020-01-28 US disclosed
US-20180087010-A1 PRE-RINSING LIQUID, PRE-RINSING TREATMENT METHOD, AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-20170351176-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, MASK BLANK INCLUDING ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2017-12-07 US disclosed
US-9250356-B2 Photochromic polymers VIVIMED LABS EUROPE LTD (GB) 2016-02-02 US disclosed
US-20140027684-A1 PHOTOCHROMIC POLYMERS VIVIMED LABS EUROPE LTD (GB) 2014-01-30 US disclosed
EP-0112718-B1 NOVEL POLYESTER, ADHESIVES COMPRISING IT, AND LAMINATES MADE OF IT KURARAY CO., LTD. (JP) 1987-03-18 EP disclosed
EP-0161021-A2 Method for the termination of living polymers and compounds suitable to that purpose ENICHEM ELASTOMERI S.p.A. (IT) 1985-11-13 EP disclosed
US-4504531-A Polyester, adhesives comprising the same, and laminates and laminated hollow vessels made thereof KURARAY CO., LTD. (JP) 1985-03-12 US disclosed
US-4496714-A CONTAINING ORGANOALUMINUM COMPOUND KURARAY CO., LTD. (JP) 1985-01-29 US disclosed
EP-0112718-A1 Novel polyester, adhesives comprising it, and laminates made of it KURARAY CO., LTD. (JP) 1984-07-04 EP disclosed
US-4113704-A Polyester filament-forming polymer and its method of production MONSANTO COMPANY (US) 1978-09-12 US disclosed
US-4092299-A MELT SPUN, PARTIALLY ORIENTED, MULTIFILAMENT MONSANTO COMPANY (US) 1978-05-30 US disclosed
US-4079046-A Multiple polyesterification process MONSANTO COMPANY, ST. LOUIS, MISSOURI (US) 1978-03-14 US disclosed