Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.68 |
| ▸ | RXRB | P28702 | 2/20 | 0.68 |
| ▸ | RXRG | P48443 | 2/20 | 0.68 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503299 | 0.87 | SRD5A2 (0.77) | RXRARXRBRXRGSRD5A2MAOB | |
| SCHEMBL402300 | 0.87 | SRD5A2 (0.87) | SRD5A2MAOBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8503301 | 0.85 | NR4A2 (0.74) | SRD5A2MAOBMAOAALDH1A1HTT | |
| SCHEMBL3232949 | 0.85 | SRD5A2 (0.90) | SRD5A2MAOBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16110081 | 0.83 | NR4A2 (0.60) | RXRARXRBRXRGSRD5A2MAOB | |
| SCHEMBL29784197 | 0.81 | RXRA (1.00) | RXRARXRBRXRGSRD5A2MAOB | |
| SCHEMBL6522344 | 0.81 | RXRA (1.00) | RXRARXRBRXRGSRD5A2MAOB | |
| SCHEMBL6521756 | 0.81 | SRD5A2 (0.62) | SRD5A2L3MBTL1PARP10POLB | |
| SCHEMBL7371119 | 0.81 | MRGPRX4 (0.64) | RXRASMN1; SMN2MRGPRX4RAB9AMEN1 | |
| SCHEMBL7908051 | 0.81 | SRD5A2 (0.85) | SRD5A2MAOBALDH1A1MRGPRX4NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | disclosed |