Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.85 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.81 |
| ▸ | MAOB | P27338 | 1/20 | 0.77 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.61 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPD | P32754 | 1/20 | 0.59 |
| ▸ | GUSB | P08236 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818111 | 0.90 | SRD5A2 (0.71) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL30207018 | 0.90 | NR4A2 (1.00) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL339009 | 0.90 | NR4A2 (1.00) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL3442746 | 0.88 | NR4A2 (0.79) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.88 | NR4A2 (0.97) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL68983 | 0.87 | MAOB (1.00) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL30412560 | 0.87 | NR4A2 (0.77) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL8189375 | 0.87 | NR4A2 (0.77) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL340107 | 0.87 | NR4A2 (0.77) | SRD5A2NR4A2MAOBSMPD1PTPN1 | |
| SCHEMBL1387246 | 0.87 | NR4A2 (0.77) | SRD5A2NR4A2MAOBSMPD1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |