Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 3/20 | 0.46 |
| ▸ | KDM4A | O75164 | 3/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.46 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.46 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784020 | 0.94 | HTT (0.46) | PTPN1KMT2AMEN1HTTKDM6B | |
| SCHEMBL10787124 | 0.90 | MEN1 (0.57) | KMT2AMEN1HTTPOLBTSHR | |
| SCHEMBL10781949 | 0.88 | THRB (0.47) | KMT2APOLBNR3C1TSHRALDH1A1 | |
| SCHEMBL6456385 | 0.84 | MEN1 (0.43) | KMT2AMEN1HTTKDM6BKDM4A | |
| SCHEMBL15659782 | 0.83 | MAPK8 (0.47) | KMT2AMEN1HTTKDM6BKDM4A | |
| SCHEMBL10786556 | 0.83 | THRB (0.48) | POLBNR3C1TSHRALDH1A1ALOX15 | |
| SCHEMBL10781993 | 0.82 | MEN1 (0.42) | KMT2AMEN1HTTKDM6BKDM4A | |
| SCHEMBL10786920 | 0.79 | THRB (0.55) | KMT2AMEN1HTTPOLBTSHR | |
| SCHEMBL11710197 | 0.78 | PDE5A (0.54) | KMT2AMEN1KDM6BKDM4AKDM4D | |
| SCHEMBL10786214 | 0.77 | MAPK8 (0.45) | KDM6BKDM4AKDM4DKDM3BHIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144730-B1 | 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND ANTIALLERGIC AGENT CONTAINING THE SAME | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0144730-A1 | 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |