Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 7/20 | 0.43 |
| ▸ | KDM4A | O75164 | 7/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 7/20 | 0.43 |
| ▸ | HIF1AN | Q9NWT6 | 7/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.43 |
| ▸ | KDM3B | Q7LBC6 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782291 | 0.89 | PDE9A (0.39) | MEN1HTTKMT2APOLBPDE9A | |
| SCHEMBL10787124 | 0.87 | MEN1 (0.57) | MEN1HTTKMT2APOLBALDH1A1 | |
| SCHEMBL10783246 | 0.87 | THRB (0.46) | POLBALDH1A1ALOX15MAPK1 | |
| SCHEMBL10781993 | 0.86 | MEN1 (0.42) | MEN1HTTKMT2AKDM6BKDM4A | |
| SCHEMBL15659782 | 0.86 | MAPK8 (0.47) | MEN1HTTKMT2AKDM6BKDM4A | |
| SCHEMBL10784090 | 0.86 | POLB (0.40) | MEN1HTTKMT2APOLBPDE9A | |
| SCHEMBL10784020 | 0.85 | HTT (0.46) | MEN1HTTKMT2AKDM6BKDM4A | |
| SCHEMBL10784690 | 0.84 | PTPN1 (0.47) | MEN1HTTKMT2AKDM6BKDM4A | |
| SCHEMBL11707410 | 0.78 | PDE5A (0.47) | KDM6BKDM4AKDM4DHIF1ANKDM2A | |
| SCHEMBL10786214 | 0.77 | MAPK8 (0.45) | KDM6BKDM4AKDM4DHIF1ANKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144730-B1 | 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND ANTIALLERGIC AGENT CONTAINING THE SAME | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1987-07-08 | — | — | EP | claimed |
| EP-0144730-A1 | 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1985-06-19 | — | — | EP | claimed |
| JP-5262747-A | — | — | None | — | — | JP | disclosed |
| JP-4305526-A | — | — | None | — | — | JP | disclosed |
| JP-6217716-A | — | — | None | — | — | JP | disclosed |
| US-20050222193-A1 | Novel combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-10-06 | — | — | US | disclosed |
| US-20050165041-A1 | Combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-07-28 | — | — | US | disclosed |
| JP-H06217716-A | ADDITIVE FOR PHARMACEUTICAL PREPARATION | MORISHITA ROUSSEL KK | 1994-08-09 | — | — | JP | disclosed |
| JP-H05262747-A | THERAPEUTIC AGENT FOR ULCERATIVE COLITIS | MORISHITA ROUSSEL KK | 1993-10-12 | — | — | JP | disclosed |
| JP-H04305526-A | MEDICINAL COMPOSITION | MORISHITA ROUSSEL KK | 1992-10-28 | — | — | JP | disclosed |
| EP-0144730-B1 | 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND ANTIALLERGIC AGENT CONTAINING THE SAME | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0144730-A1 | 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |