Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784020 | 0.91 | HTT (0.46) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL10784690 | 0.90 | PTPN1 (0.47) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL10786920 | 0.88 | THRB (0.55) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL6456385 | 0.87 | MEN1 (0.43) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL15659782 | 0.86 | MAPK8 (0.47) | MEN1KMT2AHTTALDH1A1ALOX15 | |
| SCHEMBL10781993 | 0.85 | MEN1 (0.42) | MEN1KMT2AHTTPOLB | |
| SCHEMBL10786556 | 0.81 | THRB (0.48) | ALDH1A1ALOX15MAPK1SMN1; SMN2GAA | |
| SCHEMBL10787165 | 0.81 | MAPT (0.53) | KMT2AALDH1A1ALOX15SMN1; SMN2HPGD | |
| SCHEMBL10781949 | 0.80 | THRB (0.47) | KMT2AALDH1A1ALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL10784080 | 0.80 | LMNA (0.43) | HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144730-B1 | 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND ANTIALLERGIC AGENT CONTAINING THE SAME | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0144730-A1 | 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |