Sulfuric Acid

Sulfuric Acid

SCHEMBL1078552

CC(c1ccccc1)c1ccc(O)c(C(C)c2ccccc2)c1C(C)c1ccccc1.O=S(=O)(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.34
CHRM1 known ✓ P11229 1/20 0.34
CHRM3 known ✓ P20309 1/20 0.34
ADRA1A known ✓ P35348 1/20 0.34
OPRK1 known ✓ P41145 1/20 0.34
SCN5A known ✓ Q14524 1/20 0.34
TYR P14679 1/20 0.50
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 5/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GMNN O75496 1/20 0.41
POLB P06746 1/20 0.41
PMP22 Q01453 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
VKORC1 Q9BQB6 1/20 0.39
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288556 0.92 TYR (0.58) TYRALDH1A1KDM4EKMT2ALMNA
Phosphoric Acid SCHEMBL1078532 0.87 TYR (0.50) TYRALDH1A1KDM4EKMT2ALMNA
Sulfuric Acid SCHEMBL1077500 0.87 TYR (0.46) TYRALDH1A1KDM4EKMT2ALMNA
SCHEMBL9687222 0.85 TYR (0.56) TYRALDH1A1KDM4EKMT2ALMNA
Oxirane SCHEMBL8925632 0.84 TYR (0.50) TYRALDH1A1KDM4EKMT2ALMNA
SCHEMBL9496068 0.82 TYR (0.52) TYRALDH1A1KDM4EKMT2ALMNA
Sulfuric Acid SCHEMBL28706711 0.81 TYR (0.41) TYRALDH1A1KDM4EKMT2ALMNA
SCHEMBL8369559 0.81 VKORC1 (0.39) TYRALDH1A1KDM4EKMT2ALMNA
SCHEMBL9807308 0.80 TYR (0.61) TYRALDH1A1KDM4EKMT2ALMNA
SCHEMBL8369560 0.78 TYR (0.44) TYRALDH1A1KDM4EKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2252144-B1 USE OF ESTER AMIDES AS SOLVENTS, ESTER AMIDES AS SUCH, AND METHOD FOR PREPARING ESTER AMIDES RHODIA OPERATIONS (FR) 2023-08-02 EP disclosed
WO-2019068913-A1 FORMULATIONS COMPRISING BIOLOGICALLY ACTIVE INGREDIENTS RHODIA OPERATIONS (FR) 2019-04-11 WO disclosed
US-20180072959-A1 CARBONACEOUS MATERIAL SUSPENSION RHODIA OPERATIONS (FR) 2018-03-15 US disclosed
US-20170349848-A1 SLURRY SUSPENSION COMPRISING TORREFIED WOOD PARTICLES RHODIA OPERATIONS (FR) 2017-12-07 US disclosed
US-9371273-B2 Ether-amide compounds and preparation and uses thereof RHODIA OPERATIONS (FR) 2016-06-21 US disclosed
US-20160000066-A1 Furfural derivatives as a vehicle INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) (FR) 2016-01-07 US disclosed
EP-2957623-A1 Carbonaceous material suspension Rhodia Opérations (FR) 2015-12-23 EP disclosed
US-8969621-B2 Ether-amide compounds and preparation and uses thereof RHODIA OPERATIONS (FR) 2015-03-03 US disclosed
US-20140364648-A1 ETHER-AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF RHODIA OPERATIONS (FR) 2014-12-11 US disclosed
US-8580712-B2 Bis(dialkylamide) compounds and diverse applications thereof RHODIA OPERATIONS (FR) 2013-11-12 US disclosed
US-20110263898-A1 ETHER-AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF RHODIA OPERATIONS (FR) 2011-10-27 US disclosed
US-20110014255-A1 PHYTOSANITARY FORMULATION GENERATING NANOPARTICLES, METHOD FOR PREPARING NANOPARTICLES AND USE THEREOF RHODIA OPERATIONS (FR) 2011-01-20 US disclosed
US-20100113279-A1 NOVEL BIS(DIALKYLAMIDE) COMPOUNDS AND DIVERSE APPLICATIONS THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2010-05-06 US disclosed
US-20080138370-A1 Solid Formulation Comprising a Phytosanitary Product Chimie, Rhodia 2008-06-12 US disclosed
US-5334585-A Pyrethroid microemulsion compositions and method for controlling insects therewith RHONE-POULENC CHIMIE (FR) 1994-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263898-A1 ETHER-AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF CBR3, RXRB, RER1 CHRM2 70/4885CHRM1 35/4885CHRM3 38/4885
US-20140364648-A1 ETHER-AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF RER1, RXRB, CBR3 CHRM2 87/4885CHRM1 53/4885CHRM3 46/4885
US-20160000066-A1 Furfural derivatives as a vehicle C1R, FRG1, FAR1 CHRM2 1658/4885CHRM1 298/4885CHRM3 2895/4885
US-20100113279-A1 NOVEL BIS(DIALKYLAMIDE) COMPOUNDS AND DIVERSE APPLICATIONS THEREOF C1R, CBR3, CWC15 CHRM2 683/4885CHRM1 509/4885CHRM3 1540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.