Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809626 | 0.89 | MEN1 (0.48) | PPARACETPPTGDR2TAAR1CRHBP | |
| SCHEMBL10464181 | 0.88 | PPARA (0.44) | PPARACETPPTGDR2TAAR1PYCR1 | |
| SCHEMBL9474025 | 0.86 | PPARA (0.51) | PPARACETPDAOPYCR1CRHBP | |
| SCHEMBL17508190 | 0.84 | PPARA (0.44) | PPARACETPDAOPTGDR2TAAR1 | |
| SCHEMBL10786006 | 0.83 | CRHBP (0.57) | PPARADAOTAAR1PYCR1CRHBP | |
| SCHEMBL30093228 | 0.81 | ESR1 (0.52) | PPARADAOTAAR1PYCR1CRHBP | |
| SCHEMBL10786316 | 0.80 | PYCR1 (0.48) | TAAR1PYCR1ALDH1A1 | |
| SCHEMBL12772106 | 0.79 | MEN1 (0.55) | TAAR1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL9809614 | 0.77 | HTR7 (0.44) | CETPTAAR1ALDH1A1MAPK1HTR7 | |
| Hydrochloric Acid SCHEMBL6832373 | 0.77 | PPARA (0.39) | PPARACETPPTGDR2TAAR1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145401-B1 | PHOTOCONDUCTIVE DEVICE CONTAINING NOVEL BENZYL FLUORINATED SQUARAINE COMPOUNDS | XEROX CORPORATION (US) | 1987-12-09 | — | — | EP | disclosed |
| US-4644082-A | Photoconductive devices containing novel benzyl fluorinated squaraine compositions | XEROX CORPORATION (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0145401-A2 | Photoconductive device containing novel benzyl fluorinated squaraine compounds | XEROX CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4508803-A | Photoconductive devices containing novel benzyl fluorinated squaraine compositions | XEROX CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |