Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | PKM | P14618 | 1/20 | 0.91 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.58 |
| ▸ | F13A1 | P00488 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324020 | 0.89 | LMNA (0.83) | LMNAPKMHPGDALDH1A1KMT2A | |
| SCHEMBL17117356 | 0.84 | HDAC1 (0.79) | LMNAPKMTSHRL3MBTL1HDAC1 | |
| SCHEMBL20883261 | 0.84 | HPGD (0.88) | LMNAPKMHPGDALDH1A1KMT2A | |
| SCHEMBL20883263 | 0.84 | HPGD (0.88) | LMNAPKMHPGDALDH1A1KMT2A | |
| SCHEMBL29319722 | 0.82 | LMNA (0.76) | LMNAPKMHPGDKMT2AHDAC1 | |
| SCHEMBL27418517 | 0.81 | LMNA (0.74) | LMNAPKMHPGDALDH1A1KMT2A | |
| SCHEMBL27381884 | 0.81 | HPGD (0.83) | LMNAPKMHPGDALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7869154 | 0.80 | LMNA (0.61) | LMNAPKMHPGDALDH1A1KMT2A | |
| SCHEMBL8359413 | 0.80 | LMNA (0.77) | LMNAPKMKMT2ATSHRL3MBTL1 | |
| SCHEMBL13063709 | 0.80 | LMNA (0.68) | LMNAPKMHPGDTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4658013-A | CONTAINING ALANINE, PHENYLALANINE AND/OR TYROSINE OR METHIONINE | STERLING DRUG INC. (US) | 1987-04-14 | — | — | US | disclosed |