Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20883261 | 1.00 | HPGD (0.88) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL28808203 | 0.94 | HPGD (1.00) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL10786159 | 0.84 | LMNA (0.91) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL13626338 | 0.83 | HDAC1 (0.68) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL10925762 | 0.83 | HDAC1 (0.68) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL28764825 | 0.83 | HDAC1 (0.68) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL23180466 | 0.82 | HPGD (0.73) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL27718245 | 0.81 | SMN1; SMN2 (0.66) | HPGDLMNAPKMHDAC1HDAC2 | |
| SCHEMBL7763386 | 0.81 | MEN1 (0.86) | LMNAHDAC1HDAC2ALOX5KMT2A | |
| SCHEMBL26393871 | 0.81 | HPGD (0.62) | HPGDLMNAPKMHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200290950-A1 | ALKAMIDE COMPOUNDS AND USES THEREOF | NORTH CAROLINA STATE UNIVERSITY | 2020-09-17 | — | — | US | disclosed |
| WO-2019071093-A1 | ALKAMIDE COMPOUNDS AND USES THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200290950-A1 | ALKAMIDE COMPOUNDS AND USES THEREOF | ALK, ENPP2, CYSLTR2 | HPGD 2424/4885LMNA 4044/4885PKM 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.