SCHEMBL29319722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27418517	0.87	LMNA (0.74)	LMNAPKMPOLBHPGDKMT2A
	SCHEMBL26179795	0.83	HPGD (0.58)	LMNAPKMPOLBHPGDKMT2A
	SCHEMBL23306964	0.83	LMNA (0.54)	LMNAPKMPOLBHPGDKMT2A
	SCHEMBL26707072	0.82	LMNA (0.67)	LMNAPKMHPGDHDAC3HDAC4
	SCHEMBL11236597	0.82	LMNA (0.67)	LMNAPKMPOLBHPGDKMT2A
	SCHEMBL22488362	0.82	ALB (0.54)	LMNAPKMPOLBHPGDKMT2A
	SCHEMBL24253210	0.82	ALB (0.57)	LMNAPKMHPGDKMT2APLAAT3
	SCHEMBL25730683	0.82	LMNA (0.53)	LMNAPKMPOLBHPGDKMT2A
	SCHEMBL10786159	0.82	LMNA (0.91)	LMNAPKMHPGDKMT2AHDAC3
	SCHEMBL21426817	0.82	HPGD (0.69)	POLBHPGDKMT2APLAAT3PLAAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.