Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052286 | 0.91 | TSHR (0.43) | MEN1KMT2AALDH1A1ALOX15LMNA | |
| SCHEMBL27731792 | 0.86 | PTGS2 (0.45) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL4618128 | 0.86 | TSHR (0.43) | MEN1KMT2AALDH1A1ALOX15LMNA | |
| SCHEMBL5065262 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1ALOX15LMNA | |
| 1,2-Dichlorobenzene SCHEMBL10452828 | 0.83 | TSHR (0.59) | MEN1KMT2AALDH1A1ALOX15LMNA | |
| SCHEMBL168042 | 0.83 | — | — | |
| SCHEMBL29591443 | 0.83 | — | — | |
| Formaldehyde SCHEMBL27873768 | 0.80 | TSHR (0.47) | MEN1KMT2AALDH1A1ALOX15LMNA | |
| Methyl Alcohol SCHEMBL27675375 | 0.80 | TSHR (0.47) | MEN1KMT2AALDH1A1ALOX15LMNA | |
| Phosphine SCHEMBL17580267 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107622-B1 | BENZODIOXOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1987-11-11 | — | — | EP | disclosed |
| EP-0107622-A1 | Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |