SCHEMBL5065262

SCHEMBL5065262

Fc1ccccc1F.O=S(=O)(O)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
ALOX15 P16050 1/20 0.46
LMNA P02545 2/20 0.45
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 1/20 0.42
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PSIP1 O75475 1/20 0.39
KMT2A Q03164 5/20 0.38
HPGD P15428 1/20 0.38
MEN1 O00255 3/20 0.38
GAA P10253 1/20 0.38
RECQL P46063 1/20 0.38
ACHE P22303 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL791706 0.88 ALDH1A1 (0.46) ALDH1A1ALOX15LMNACES2CES1
SCHEMBL10786283 0.85 MEN1 (0.40) ALDH1A1ALOX15LMNACES2CES1
SCHEMBL5014198 0.84 CES2 (0.48) ALDH1A1ALOX15LMNACES2CES1
SCHEMBL9229864 0.84 ACHE (0.65) ALDH1A1ALOX15LMNACES2CES1
Sulfuric Acid SCHEMBL28200869 0.83 CES2 (0.44) ALDH1A1ALOX15LMNACES2CES1
SCHEMBL27523713 0.83 ACHE (0.43) ALDH1A1ALOX15LMNACES2CES1
Fluorobenzene SCHEMBL974376 0.81 TSHR (0.46) ALDH1A1SMN1; SMN2HSD17B10TDP1TSHR
SCHEMBL27684435 0.79 LMNA (0.44) ALDH1A1ALOX15LMNACES2CES1
SCHEMBL27792597 0.79 PSIP1 (0.50) ALDH1A1ALOX15LMNACES2CES1
Benzene SCHEMBL6008819 0.79 CES2 (0.44) ALDH1A1ALOX15LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080090972-A1 Oligomers and Polymers Containing Sulfinate Groups, and Methods for Producing the Same KERRES JOCHEN 2008-04-17 US disclosed
US-7288599-B2 Oligomers and polymers containing sulfinate groups, and method for producing the same KERRES JOCHEN 2007-10-30 US disclosed
US-20050165172-A1 Oligomers and polymers containing sulfinate groups, and method for producing the same KERRES JOCHEN (DE) 2005-07-28 US disclosed