Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788513 | 1.00 | PTGS2 (0.55) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL17132056 | 1.00 | PTGS2 (0.55) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL10789776 | 1.00 | PTGS2 (0.55) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL5821732 | 0.98 | PTGS2 (0.54) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL10728370 | 0.91 | MAPK1 (0.54) | PTGS2CYP3A4GPR84LMNATP53 | |
| SCHEMBL14681829 | 0.90 | PTGS2 (0.50) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL11732278 | 0.86 | PTGS2 (0.47) | PTGS2CYP3A4GPR84KCNH2NPC1 | |
| SCHEMBL10456934 | 0.81 | NOS3 (0.39) | PTGS2CYP3A4KDM4EALDH1A1LMNA | |
| SCHEMBL8560359 | 0.81 | PTGS2 (0.70) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL7628223 | 0.81 | PTGS2 (0.70) | PTGS2CYP3A4GPR84ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562253-A | Deacylation of amides | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1985-12-31 | — | — | US | claimed |
| EP-4245295-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR USE IN TREATING RETINA-ASSOCIATED DISEASE USING CCR3-INHIBITORS | Alkahest, Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| EP-0108034-B1 | DEACYLATION OF AMIDES | BIOCHEMIE Gesellschaft m.b.H. (AT) | 1987-01-28 | — | — | EP | disclosed |
| US-4562253-A | Deacylation of amides | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1985-12-31 | — | — | US | disclosed |
| EP-0108034-A2 | Deacylation of amides | BIOCHEMIE Gesellschaft m.b.H. (AT) | 1984-05-09 | — | — | EP | disclosed |