Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.86 |
| ▸ | TSHR | P16473 | 2/20 | 0.86 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.86 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.86 |
| ▸ | KDR | P35968 | 1/20 | 0.86 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.86 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.70 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylparaben SCHEMBL28614294 | 0.98 | ESR1 (0.83) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL11484158 | 0.95 | ALDH1A1 (0.78) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL977 | 0.93 | ESR1 (1.00) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL429594 | 0.93 | ESR1 (1.00) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| SCHEMBL1995221 | 0.93 | LMNA (0.75) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Terephthalic Acid SCHEMBL28622229 | 0.93 | LMNA (0.75) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL6129826 | 0.91 | ALDH1A1 (0.89) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL5671589 | 0.91 | ESR1 (0.96) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL1010568 | 0.91 | ESR1 (0.96) | ESR1ALDH1A1TSHRCHRM1SLC6A2 | |
| Propylparaben SCHEMBL8779117 | 0.91 | ESR1 (0.96) | ESR1ALDH1A1TSHRCHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275974-A1 | Pharmaceutical Composition Of Piperazine Derivatives | UCB, S.A. (BE) | 2007-11-29 | — | — | US | claimed |
| EP-1768649-A2 | PHARMACEUTICAL COMPOSITION OF PIPERAZINE DERIVATIVES | UCB Farchim S.A. (CH) | 2007-04-04 | — | — | EP | claimed |
| WO-2006005507-A2 | PHARMACEUTICAL COMPOSITION OF PIPERAZINE DERIVATIVES | UCB FARCHIM SA (CH) | 2006-01-19 | — | — | WO | claimed |
| WO-2023069455-A1 | MESEMBRINE DERIVATIVES | KIRKLAND JUSTIN (US) | 2023-04-27 | — | — | WO | disclosed |
| US-20220265552-A1 | ESLICARBAZEPINE SUSPENSION | Jubilant Generics Limited (IN) | 2022-08-25 | — | — | US | disclosed |
| US-11318145-B2 | Eslicarbazepine suspension | Jubilant Generics Limited | 2022-05-03 | — | — | US | disclosed |
| US-20210275539-A1 | ESLICARBAZEPINE SUSPENSION | Jubilant Generics Limited (IN) | 2021-09-09 | — | — | US | disclosed |
| EP-3716944-A1 | STABLE LIQUID COMPOSITION OF KETOPROFEN, SALTS AND ENANTIOMERS THEREOF | Aziende Chimiche Riunite Angelini Francesco A.C.R. (IT) | 2020-10-07 | — | — | EP | disclosed |
| US-20200281879-A1 | STABLE LIQUID COMPOSITION OF KETOPROFEN, SALTS AND ENANTIOMERS THEREOF | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2020-09-10 | — | — | US | disclosed |
| EP-2349242-B1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS INC (US) | 2018-12-05 | — | — | EP | disclosed |
| EP-2906672-A1 | SELF-THICKENING DETERGENTS | Henkel AG&Co. KGAA (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1207854-A1 | PRESERVED LIPOSOMES | Arch Personal Care Products, L.P. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001017507-A1 | PRESERVED LIPOSOMES | ARCH PERSONAL CARE PRODUCTS, L.P. (US) | 2001-03-15 | — | — | WO | disclosed |
| US-6083854-A | COMPRISING WIPE SUBSTRATE HAVING EMULSION COMPRISING WATER, SILICONE BASE, POLYMER, STABILIZER PHENOXYETHANOL; USED FOR SKIN CARE, MAKE-UP REMOVAL; BABY CARE PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0967968-A1 | PHARMACEUTICAL OR COSMETIC COMPOSITION CONTAINING AT LEAST ONE RETINOID | ROC (FR) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038980-A1 | PHARMACEUTICAL OR COSMETIC COMPOSITION CONTAINING AT LEAST ONE RETINOID | ROC (FR) | 1998-09-11 | — | — | WO | disclosed |
| US-5676934-A | SUNSCREEN ACTIVE MATERIAL, BIOCIDE, ANTIOXIDANT, POLYVINYLPYRROLIDINE SUBSTANTIVE AID, EMOLLIENT, SOLVENT, ACRYLATE ENTRAPMENT POLYMER; DRY POWDER | INTERNATIONAL CREATIONS, LTD. (US) | 1997-10-14 | — | — | US | disclosed |
| US-4536399-A | THICKENING AGENT, SODIUM LAURYL SUFLATE EMULSIFIER | NORCLIFF THAYER, INC. (US) | 1985-08-20 | — | — | US | disclosed |
| US-4400378-A | THIAZOLO OR OXAZOLO COMPOUNDS | KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-08-23 | — | — | US | disclosed |
| US-3932622-A | WATER-IN-OIL EMULSION, DISODIUM OR DIPOTASSIUM SALT OF N-ACETYLGLUTAMTIC ACID | GENERAL FOODS CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275974-A1 | Pharmaceutical Composition Of Piperazine Derivatives | PAK5, P2RX5, IL5 | ESR1 4197/4885ALDH1A1 171/4885TSHR 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.