SCHEMBL10787019

SCHEMBL10787019

CCCCCCCCCCCCCCCCCCNC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.61
ALDH1A1 P00352 2/20 0.48
THRB P10828 1/20 0.48
PYGB P11216 4/20 0.46
GBA1 P04062 6/20 0.45
GAA P10253 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CD69 Q07108 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10529893 1.00 MAPK1 (0.61) MAPK1ALDH1A1THRBPYGBGBA1
SCHEMBL23136470 1.00 MAPK1 (0.61) MAPK1ALDH1A1THRBPYGBGBA1
SCHEMBL10625975 1.00 MAPK1 (0.61) MAPK1ALDH1A1THRBPYGBGBA1
SCHEMBL24645911 0.95 MAPK1 (0.57) MAPK1ALDH1A1THRBPYGBGAA
SCHEMBL10598091 0.88 PYGB (0.53) MAPK1PYGBGBA1GAA
SCHEMBL10812315 0.88 PYGB (0.53) MAPK1PYGBGBA1GAA
SCHEMBL16217898 0.84 ALDH1A1 (0.54) MAPK1ALDH1A1THRBPYGBGAA
SCHEMBL22692620 0.81 MAPK1 (0.58) MAPK1ALDH1A1THRBPYGBGAA
SCHEMBL5498712 0.81 MAPK1 (0.57) MAPK1ALDH1A1THRBPYGBGAA
SCHEMBL5498717 0.81 MAPK1 (0.57) MAPK1ALDH1A1THRBPYGBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4710491-A N-glycosylated carboxylic acid derivatives as agents for combating rheumatic diseases TROPONWERKE GMBH & CO., KG (DE) 1987-12-01 US disclosed
US-4683222-A STIMULANTS FOR IMMUNE SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1987-07-28 US disclosed
US-4680287-A N-glycosylated carboxamide derivatives as growth-promoters in livestock feeding BAYER AKTIENGESELLSCHAFT (DE) 1987-07-14 US disclosed
EP-0091645-B1 DERIVATIVES OF AMIDES OF CARBOXYLIC ACIDS IN WHICH THE N ATOM IS SUBSTITUTED BY A GLYCOSYL RADICAL, METHOD FOR THEIR PREPARATION AND THEIR USE TO INFLUENCE THE IMMUNOGENIC SYSTEM BAYER AG (DE) 1987-02-25 EP disclosed
EP-0147777-A2 Derivatives of M-glycosylated amides of carboxylic acids as a product for combating diseases of the rheumatism type Troponwerke GmbH & Co. KG (DE) 1985-07-10 EP disclosed
EP-0140321-A2 Use of derivatives of amides of carboxylic acids in which the N atom is substituted by a glycosyl radical as growth promotor in animal nutrition BAYER AG (DE) 1985-05-08 EP disclosed
EP-0091645-A1 Derivatives of amides of carboxylic acids in which the N atom is substituted by a glycosyl radical, method for their preparation and their use to influence the immunogenic system BAYER AG (DE) 1983-10-19 EP disclosed