Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PYGB | P11216 | 3/20 | 0.42 |
| ▸ | CD69 | Q07108 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498717 | 1.00 | MAPK1 (0.57) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL7123019 | 1.00 | MAPK1 (0.57) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL22692620 | 0.89 | MAPK1 (0.58) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL22227281 | 0.87 | MAPK1 (0.55) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL23016466 | 0.83 | MAPK1 (0.53) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL5494068 | 0.82 | PYGB (0.47) | MAPK1CA1CA2CA9PYGB | |
| SCHEMBL5494071 | 0.82 | PYGB (0.47) | MAPK1CA1CA2CA9PYGB | |
| SCHEMBL10529883 | 0.82 | MAPK1 (0.58) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL20099370 | 0.81 | ALDH1A1 (0.54) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL10787019 | 0.81 | MAPK1 (0.61) | MAPK1ALDH1A1THRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312194-B2 | Delivery systems | ALCHEMIA PTY. LTD. (AU) | 2007-12-25 | — | — | US | disclosed |
| US-20040176281-A1 | Delivery systems | ALCHEMIA LIMITED (AU) | 2004-09-09 | — | — | US | disclosed |
| WO-2002053572-A1 | DELIVERY SYSTEMS | ALCHEMIA PTY LTD (AU) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176281-A1 | Delivery systems | MTX2, SGMS2, SGMS1 | MAPK1 4773/4885ALDH1A1 2447/4885THRB 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.