Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10234302 | 0.84 | L3MBTL1 (0.46) | HDAC6HDAC3NCOR2LOXL2KDM4E | |
| Hydrochloric Acid SCHEMBL13738814 | 0.83 | GSK3B (0.42) | HDAC6HDAC3KDM4EALDH1A1ABL1 | |
| SCHEMBL10789245 | 0.83 | PRSS1 (0.47) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL14230567 | 0.81 | MAPT (0.54) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL13844915 | 0.81 | PRSS1 (0.48) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL8744803 | 0.80 | ALDH1A1 (0.59) | LOXL2KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10788688 | 0.79 | NPC1 (0.48) | PRSS1PRSS2PRSS3MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL22556739 | 0.78 | ALDH1A1 (0.57) | LOXL2KDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10789237 | 0.78 | PRSS1 (0.52) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL10234308 | 0.78 | ALDH1A1 (0.45) | MMP2HDAC6HDAC3NCOR2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| EP-4532484-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2025-04-09 | — | — | EP | disclosed |
| CN-119173509-A | ROCK inhibitors and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-12-20 | — | — | CN | disclosed |
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| US-4683330-A | ANTICOAGULANTS, ANTIULCER AGENTS | THE UPJOHN COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| US-4668814-A | ANTIULCER AGENTS, ANTIASHMATICS, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4628110-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| US-4621100-A | Treatment of osteoporosis with prostaglandins | THE UPJOHN COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0089769-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-10-01 | — | — | EP | disclosed |
| EP-0092352-B1 | 9-SUBSTITUTED CARBACYCLINS | THE UPJOHN COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4218378-A | 11a-Methano-TXA compounds | THE UPJOHN COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| US-4160095-A | PROSTAGLANDINS; ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1979-07-03 | — | — | US | disclosed |
| US-4157441-A | PROSTAGLANDINS, ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4151351-A | PROSTAGLANDINS, ANTIINFLAMMATORY | THE UPJOHN COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | ROCK1, ROCK2, RHOA | PRSS1 2663/4885PRSS2 3974/4885PRSS3 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.