Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792862 | 0.80 | CA1 (0.35) | CA1CA2CYP3A4TP53PTGS2 | |
| SCHEMBL9304980 | 0.78 | GABRA1 (0.39) | CA1CA2ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL8352460 | 0.78 | SMN1; SMN2 (0.52) | CA1CA2ALDH1A1ALOX15CYP3A4 | |
| Lithium Ion SCHEMBL6312687 | 0.75 | CA1 (0.59) | CA1CA2ALDH1A1GAAALOX15 | |
| SCHEMBL10790668 | 0.75 | CA1 (0.43) | CA1CA2ALDH1A1GAALMNA | |
| SCHEMBL10792703 | 0.73 | HSPA5 (0.49) | CA1CA2ALDH1A1GAAALOX15 | |
| SCHEMBL39130 | 0.73 | CA2 (1.00) | CA1CA2ALDH1A1GAAALOX15 | |
| SCHEMBL10957455 | 0.71 | CA2 (0.50) | CA1CA2ALDH1A1ALOX15LMNA | |
| SCHEMBL10791312 | 0.70 | GAA (0.38) | ALDH1A1GAAALOX15CYP3A4LMNA | |
| SCHEMBL22360314 | 0.70 | CA1 (0.64) | CA1CA2ALDH1A1GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128368-B1 | 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES | The B.F. GOODRICH Company (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4590017-A | 2,4-bis-(2,6-di-t-alkyl-4-substituted-phenoxy)-1,3,2,4-dioxadiphosphetanes | THE B. F. GOODRICH COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4515733-A | Method for making 1,3,5,2,4,6-trioxatriphosphorinanes | THE B. F. GOODRICH CO. (US) | 1985-05-07 | — | — | US | disclosed |
| US-4507416-A | 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes as stabilizers | THE B. F. GOODRICH COMPANY (US) | 1985-03-26 | — | — | US | disclosed |