Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.36 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356245 | 0.90 | POLB (0.38) | GABRA1GABRB2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL7640191 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL8352460 | 0.83 | SMN1; SMN2 (0.52) | ALDH1A1ALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL28891370 | 0.78 | POLB (0.41) | GABRA1GABRB2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL10792703 | 0.78 | HSPA5 (0.49) | ALDH1A1ALOX15CYP1A2SMN1; SMN2GABBR2 | |
| SCHEMBL10789482 | 0.78 | CA1 (0.57) | ALDH1A1ALOX15CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL10957455 | 0.76 | CA2 (0.50) | GABRA1GABRB2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL10791312 | 0.75 | GAA (0.38) | ALDH1A1ALOX15CYP1A2SMN1; SMN2GABBR2 | |
| SCHEMBL10791276 | 0.74 | LMNA (0.40) | HSP90AA1LMNA | |
| SCHEMBL10792862 | 0.74 | CA1 (0.35) | CA2CA1CYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515733-A | Method for making 1,3,5,2,4,6-trioxatriphosphorinanes | THE B. F. GOODRICH CO. (US) | 1985-05-07 | — | — | US | claimed |
| US-5308901-A | Oxidation resistant, photostabilizers for polymers | GENERAL ELECTRIC COMPANY (US) | 1994-05-03 | — | — | US | disclosed |
| US-5137950-A | Reacting phosphorous trichloride with alcohol; polymer stabilizer | BORG-WARNER SPECIALTY CHEMICALS, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-5023285-A | Melt flow and color stabilizers for polymers | G E SPECIALTY CHEMICALS (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0106169-B1 | SUBSTITUTED 2-(2,6-DI-T-BUTYL-4-ALKYLPHENOXY) 4H-1,3,2-BENZODIOXAPHOSPHORINS AND COMPOSITIONS THEREOF | The B.F. GOODRICH Company (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0128368-B1 | 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES | The B.F. GOODRICH Company (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4590017-A | 2,4-bis-(2,6-di-t-alkyl-4-substituted-phenoxy)-1,3,2,4-dioxadiphosphetanes | THE B. F. GOODRICH COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4529533-A | Substituted 2-(2,6-di-t-butly-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| US-4515733-A | Method for making 1,3,5,2,4,6-trioxatriphosphorinanes | THE B. F. GOODRICH CO. (US) | 1985-05-07 | — | — | US | disclosed |
| US-4507416-A | 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes as stabilizers | THE B. F. GOODRICH COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| EP-0128368-A1 | 2,4,6-Tris(substituted phenoxy)-1,3,5,2,4,6-trioxatriphosphorinanes | The B.F. GOODRICH Company (US) | 1984-12-19 | — | — | EP | disclosed |
| EP-0110293-A2 | Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof | The B.F. GOODRICH Company (US) | 1984-06-13 | — | — | EP | disclosed |
| EP-0106169-A1 | Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-25 | — | — | EP | disclosed |
| EP-0104643-A2 | 5-Membered cyclic phosphonates and compositions thereof | The B.F. GOODRICH Company (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4439564-A | 5-Membered cyclic phosphonates and compositions thereof | THE B. F. GOODRICH CO. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4415686-A | Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1983-11-15 | — | — | US | disclosed |