Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14696701 | 0.77 | HSP90AA1 (0.54) | POLBMEN1KMT2AMAPTHSP90AA1 | |
| SCHEMBL23400530 | 0.77 | NR3C2 (0.43) | KDM4EMEN1KMT2ATP53HTT | |
| SCHEMBL14696532 | 0.77 | HSP90AA1 (0.44) | GAAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1631545 | 0.73 | HSP90AA1 (0.47) | KMT2AHSP90AA1 | |
| SCHEMBL12273672 | 0.73 | KDM4E (0.42) | POLBGAAKDM4EMEN1KMT2A | |
| SCHEMBL10666477 | 0.72 | CA12 (0.46) | POLBGAAKDM4EMEN1KMT2A | |
| SCHEMBL5579308 | 0.71 | POLB (0.57) | POLBGAAKDM4EKEAP1TSHR | |
| SCHEMBL1628677 | 0.71 | HSP90AA1 (0.51) | POLBGAAKDM4EALOX15TSHR | |
| SCHEMBL4461012 | 0.69 | GAA (0.48) | POLBGAAKDM4EMEN1KMT2A | |
| SCHEMBL10790675 | 0.68 | POLB (0.44) | POLBMEN1KMT2AHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649194-A | 1:2 metal complexes of a disazo compound having a 5-hydroxy-1-(aminophenyl)pyrazole coupling/diazo component radical and disazo compound having a 1-amino-8-hydroxynaphthalene coupling/diazo component | SANDOZ LTD. (CH) | 1987-03-10 | — | — | US | disclosed |