Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829749 | 0.82 | MAPK9 (0.42) | POLBCYP2C9KDM4ELMNA | |
| SCHEMBL14696217 | 0.78 | KDM4E (0.42) | POLBKDM4ENR3C2 | |
| SCHEMBL10790675 | 0.78 | POLB (0.44) | POLBCYP2C9CYP2C19CYP2C18LMNA | |
| SCHEMBL23401516 | 0.78 | ALDH1A1 (0.44) | CYP2C9HSP90AA1CYP2C19CYP2C18LMNA | |
| SCHEMBL14696791 | 0.77 | NR3C2 (0.46) | POLBKEAP1NR3C2NPC1 | |
| SCHEMBL23399997 | 0.77 | KMT2A (0.48) | POLBGAAKDM4EHSP90AA1LMNA | |
| SCHEMBL15663976 | 0.77 | NR3C2 (0.47) | POLBGAAKDM4ETDP1NR3C2 | |
| SCHEMBL28391996 | 0.75 | POLB (0.50) | POLBCYP2C9GAACYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL10340598 | 0.75 | KMT2A (0.47) | POLBGAAKDM4EHSP90AA1LMNA | |
| SCHEMBL28814054 | 0.74 | LMNA (0.43) | KDM4EHSP90AA1LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956843-A | High-elasticity-recovery-rate low-temperature-resistant asphalt pavement crack pouring adhesive | 梁昌云 | 2022-01-21 | — | — | CN | claimed |
| CN-104458601-A | Fiber identification coloring agent and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2015-03-25 | — | — | CN | claimed |
| US-4400317-A | NO NEED TO PRECIPITATE PRODUCT FROM REACTION SOLUTION | AMERICAN HOECHST CORPORATION (US) | 1983-08-23 | — | — | US | claimed |
| CN-122036691-A | 3-Phenyl-1H-pyrazol-5-alcohol spliced indole derivatives, and preparation method and application thereof | 遵义医药高等专科学校 | 2026-05-15 | — | — | CN | disclosed |
| WO-2025062334-A1 | 4-((5-(3-(4-(PYRIDIN-2-YL)CYCLOPENTYL)-1 H-PYRAZOL-3-YL)AMINO)-BENZENESULFONAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER | BEIGENE SWITZERLAND GMBH (CH) | 2025-03-27 | — | — | WO | disclosed |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | SHANGHAI EAST HOSPITAL (CN) | 2025-01-07 | — | — | US | disclosed |
| US-20230015875-A1 | Ion Channel Antagonists/Blockers and Uses Thereof | SHANGHAI EAST HOSPITAL (CN) | 2023-01-19 | — | — | US | disclosed |
| CN-113956843-A | High-elasticity-recovery-rate low-temperature-resistant asphalt pavement crack pouring adhesive | 梁昌云 | 2022-01-21 | — | — | CN | disclosed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| CN-108658867-A | A kind of synthetic method of the ketone compounds of pyrazoline containing benzenesulfonyl | 青岛农业大学 | 2018-10-16 | — | — | CN | disclosed |
| CN-104059020-B | The preparation method of 1-aryl-5-hydroxypyrazoles | 湖南海利常德农药化工有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104059020-A | Preparation method for 1-aryl-5-hydroxy pyrazol | HUNAN HAILI CHANGDE PESTICIDE & CHEMICAL INDUSTRY CO LTD | 2014-09-24 | — | — | CN | disclosed |
| US-8569346-B1 | Thiazoline ring compounds as botulinum antagonists | BIOMADISON, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |
| US-4531005-A | Pyrazol-4-yl phosphites | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-07-23 | — | — | US | disclosed |
| US-4400317-A | NO NEED TO PRECIPITATE PRODUCT FROM REACTION SOLUTION | AMERICAN HOECHST CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230015875-A1 | Ion Channel Antagonists/Blockers and Uses Thereof | CACNA1F, CACNA1S, CACNA1D | POLB 3830/4885CYP2C9 879/4885GAA 914/4885 |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | CACNA1F, CACNA1S, CACNA1D | POLB 3830/4885CYP2C9 879/4885GAA 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.