Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.40 |
| ▸ | CYP2C18 | P33260 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401516 | 0.79 | ALDH1A1 (0.44) | CYP2C9CYP2C18LMNACYP3A4CYP2C19 | |
| SCHEMBL14696217 | 0.79 | KDM4E (0.42) | POLBMEN1KMT2A | |
| SCHEMBL29829749 | 0.78 | MAPK9 (0.42) | POLBCYP2C9LMNAMAPTALDH1A1 | |
| SCHEMBL5579308 | 0.78 | POLB (0.57) | POLBCYP2C9CYP2C18LMNACYP3A4 | |
| SCHEMBL20001726 | 0.75 | HIF1A (0.41) | POLBHSD17B10CYP2C19TDP1MAPT | |
| SCHEMBL15293588 | 0.73 | LMNA (0.45) | POLBCYP2C9CYP2C18LMNACYP3A4 | |
| SCHEMBL1630310 | 0.71 | MEN1 (0.40) | POLBCYP3A4HSD17B10MAPTALDH1A1 | |
| SCHEMBL4886599 | 0.71 | KDM4E (0.47) | POLBCYP2C9CYP2C18LMNACYP3A4 | |
| SCHEMBL23399161 | 0.71 | ALDH1A1 (0.45) | CYP2C9LMNACYP3A4HSD17B10CYP2C19 | |
| SCHEMBL19240299 | 0.69 | POLB (0.52) | POLBCYP2C9CYP2C18LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649194-A | 1:2 metal complexes of a disazo compound having a 5-hydroxy-1-(aminophenyl)pyrazole coupling/diazo component radical and disazo compound having a 1-amino-8-hydroxynaphthalene coupling/diazo component | SANDOZ LTD. (CH) | 1987-03-10 | — | — | US | disclosed |