Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389918 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2FFAR1CYP1A2LMNARAB9A | |
| SCHEMBL11507229 | 0.86 | BCAT2 (0.57) | SMN1; SMN2LMNABCAT2KMT2ACHRNB2 | |
| SCHEMBL11244471 | 0.85 | BCAT2 (0.60) | SMN1; SMN2BCAT2KMT2ACHRNB2CHRNB4 | |
| SCHEMBL3630027 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNABCAT2KMT2ACHRNB2 | |
| SCHEMBL8618099 | 0.83 | BCAT2 (0.53) | SMN1; SMN2LMNABCAT2KMT2ACHRNB2 | |
| SCHEMBL27707879 | 0.82 | NR4A2 (0.43) | SMN1; SMN2FFAR1CYP1A2LMNARAB9A | |
| SCHEMBL4529250 | 0.82 | BCAT2 (0.61) | SMN1; SMN2LMNABCAT2KMT2ACHRNB2 | |
| SCHEMBL28023427 | 0.81 | GPR52 (0.56) | SMN1; SMN2FFAR1RAB9ABCAT2KMT2A | |
| SCHEMBL27539512 | 0.81 | BCAT2 (0.55) | SMN1; SMN2LMNABCAT2KMT2ACHRNB2 | |
| SCHEMBL30522208 | 0.80 | LTB4R2 (0.55) | SMN1; SMN2BCAT2KMT2ACHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180290-B1 | OMEGA-(2',4'-DIHALOBIPHENYLYL)OXO ALKANOIC ACIDS AND PROCESS FOR THEIR PREPARATION | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1987-10-28 | — | — | EP | disclosed |
| US-4683331-A | ANTIINFLAMMATORY | SPOFA SPOJENE PODNIKY PRO ZDRAVOTNICKOU (CS) | 1987-07-28 | — | — | US | disclosed |
| EP-0180290-A1 | Omega-(2',4'-dihalobiphenylyl)oxo alkanoic acids and process for their preparation | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1986-05-07 | — | — | EP | disclosed |
| EP-0010347-B1 | NOVEL SUBSTITUTED OMEGA-AROYL(PROPIONYL OR BUTYRYL)-L-PROLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |
| US-4226775-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0010347-A1 | Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |