Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507229 | 0.89 | BCAT2 (0.57) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8148053 | 0.86 | LTB4R2 (0.55) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30522208 | 0.86 | LTB4R2 (0.55) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8820695 | 0.84 | BCAT2 (0.53) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9551671 | 0.84 | SOAT1 (0.56) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10790803 | 0.83 | SMN1; SMN2 (0.56) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11244471 | 0.83 | BCAT2 (0.60) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28743866 | 0.83 | SOAT1 (0.58) | BCAT2MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL28003347 | 0.83 | SOAT1 (0.58) | BCAT2MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL4446464 | 0.82 | GPR52 (0.48) | BCAT2CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807899-A | Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0839130-A1 | TRIPHENYL ETHYLENES WITH ANTI-OESTROGENIC PROPERTIES | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003046-A1 | TRIPHENYL ETHYLENES WITH ANTI-OESTROGENIC PROPERTIES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-01-30 | — | — | WO | disclosed |