Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 9/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503126 | 0.83 | KDR (0.50) | KDRNOTUMPDK1CA1CA2 | |
| SCHEMBL11285214 | 0.82 | IDO1 (0.39) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14303602 | 0.82 | NOTUM (0.49) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20308687 | 0.75 | KIF11 (0.44) | — | |
| SCHEMBL21378321 | 0.74 | KDR (0.49) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22168116 | 0.73 | AR (0.66) | — | |
| SCHEMBL29649700 | 0.73 | IDO1 (0.50) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2698021 | 0.73 | NOTUM (0.61) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL987352 | 0.73 | IDO1 (0.50) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5013607 | 0.72 | AHR (0.46) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354126-A1 | Heteroaryl sulfonamides and CCR2 | ChemoCentryx, Inc. (US) | 2011-08-10 | — | — | EP | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |
| US-4514566-A | INSECTICIDES, MOLLUSCICIDES, MITICIDES AND NEMATOCIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0058346-B1 | N SULFENYL OXIMECARBAMATES, PREPARATION THEREOF AND USE THEREOF AS PESTICIDE | BAYER AG (DE) | 1985-01-16 | — | — | EP | disclosed |
| US-4470984-A | Combating pests with novel oxime-carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| US-4427687-A | INSECTICIDES, MITICIDES, AND MOLLUSCICIDES | HOFFMANN-LA ROCHE INC. (US) | 1984-01-24 | — | — | US | disclosed |
| EP-0083744-A2 | Oxime carbamates, the process for their production, their use as biocides, intermediates for their production and process for producing these intermediates | BAYER AG (DE) | 1983-07-20 | — | — | EP | disclosed |
| US-4359469-A | Combating pests with N-sulphenylated oxime-carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| US-4344953-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0005249-B1 | SUBSTITUTED ALKANYL-AZOLYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES, ACARICIDES AND NEMATOCIDES | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4117154-A | INSECTICIDES, ACARICIDES, NEMATOCIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |