Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255135 | 0.80 | FBP1 (0.57) | AHRTP53HAO1TSHRCYP3A4 | |
| SCHEMBL10957865 | 0.80 | HAO1 (0.53) | AHRTP53HAO1TSHRCYP3A4 | |
| SCHEMBL18680750 | 0.77 | RAPGEF4 (0.35) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL4120274 | 0.77 | MEN1 (0.39) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL24805337 | 0.76 | AHR (0.43) | AHRTP53HAO1TSHRCYP3A4 | |
| SCHEMBL1145367 | 0.76 | AHR (0.43) | AHRTP53HAO1TSHRCYP3A4 | |
| SCHEMBL1145370 | 0.76 | AHR (0.43) | AHRTP53HAO1TSHRCYP3A4 | |
| SCHEMBL9515929 | 0.74 | TDP1 (0.45) | AHRTP53HAO1TSHRCYP3A4 | |
| SCHEMBL10794853 | 0.72 | IDO1 (0.44) | IDO1 | |
| SCHEMBL20756137 | 0.72 | TRPV4 (0.53) | CYP3A4MEN1KMT2AIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| EP-1890993-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR ANTAGONISTS OF GLYR | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006121390-A2 | BENZOIC ACID DERIVATIVES THAT ARE MODULATORS OR AGONISTS OF GLYR | ASTRAZENECA AB (SE) | 2006-11-16 | — | — | WO | disclosed |
| EP-0949249-B1 | PROCESS FOR PRODUCING IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |
| EP-0432471-A1 | Novel chloroacetamide derivates and processes for the production of the same and the use thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |
| US-4562185-A | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0126235-A1 | Five-membered nitrogen-containing heterocycles, process for their preparation and their use as pesticides | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4172131-A | Pesticidally active N-(alkoxy-alkylthio-thiophosphoryl)-N-substituted-N-arylthio-formamidines | BAYER AKTIENGESELLCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |