Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 17/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11908592 | 0.77 | KDM4E (0.53) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL14467198 | 0.75 | KDM4E (0.46) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL19732953 | 0.75 | ADORA2B (0.78) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL19732954 | 0.75 | ADORA2B (0.78) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL28070114 | 0.75 | ADORA2B (0.60) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL19752683 | 0.70 | ADORA2B (1.00) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL5347733 | 0.70 | ADORA2B (1.00) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL4056038 | 0.69 | GAA (0.54) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL12464054 | 0.69 | GAA (0.54) | ADORA2BPOLBL3MBTL1TDP1KDM4E | |
| SCHEMBL13527924 | 0.69 | TDP1 (0.80) | TDP1KDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044777-A1 | HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | disclosed |
| US-4692513-A | FOODS AND BEVERAGES | THE PROCTER & GAMBLE COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4692512-A | FOODS AND BEVERAGES | THE PROCTER & GAMBLE COMPANY (US) | 1987-09-08 | — | — | US | disclosed |