SCHEMBL1079489

SCHEMBL1079489

[CH2]C(C(=C)C(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.35
TET3 O43151 1/20 0.35
TET1 Q8NFU7 1/20 0.35
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
TDP1 Q9NUW8 1/20 0.30
TSHR P16473 1/20 0.30
LMNA P02545 1/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168567 0.75
SCHEMBL4261212 0.72
SCHEMBL4733794 0.72 ALDH1A1 (0.38) TDP1TSHRLMNAALDH1A1THRB
SCHEMBL12489061 0.72 ALDH1A1 (0.38) TDP1TSHRLMNAALDH1A1THRB
SCHEMBL28927469 0.71 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL4368045 0.71 LMNA (0.32) TET2TET3TET1TDP1TSHR
SCHEMBL758998 0.69 TET2 (0.40) TET2TET3TET1GRIK1GRIK2
SCHEMBL1230378 0.67
SCHEMBL5293647 0.67 GRIK1 (0.42) TET2TET3TET1GRIK1GRIK2
SCHEMBL14533362 0.67 HPGD (0.40) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110018151-A1 Method for Producing Wafer Lens KONICA MINOLTA OPTO, INC. (JP) 2011-01-27 US disclosed