Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747292 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HPGDGAANPSR1LMNA | |
| SCHEMBL11374454 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDGAANPSR1LMNA | |
| SCHEMBL11378848 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDGAANPSR1LMNA | |
| SCHEMBL3077238 | 0.77 | TAS2R38 (0.40) | ALDH1A1HPGDHSD17B10GAANPSR1 | |
| SCHEMBL6947071 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL329850 | 0.75 | — | — | |
| SCHEMBL437705 | 0.74 | NPSR1 (0.44) | ALDH1A1HPGDGAANPSR1LMNA | |
| SCHEMBL12703379 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HPGDGAANPSR1LMNA | |
| SCHEMBL1770104 | 0.73 | ALDH1A1 (0.49) | ALDH1A1HPGDGAANPSR1LMNA | |
| Iodide SCHEMBL31261479 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231915-A2 | Thermoplastic elastomers containing cross-linked epihalohydrin rubbers | HERCULES INCORPORATED (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4624989-A | BLENDING RUBBER, POLYOLEFIN, CHLORINATED HYDROCARBON; PREFERENTIAL CROSSLINKING | HERCULES INCORPORATED (US) | 1986-11-25 | — | — | US | disclosed |
| US-4268640-A | CURING AGENT OF MONO OR DI-THIOBIUREA | OSAKA SODA CO. LTD. (JP) | 1981-05-19 | — | — | US | disclosed |