SCHEMBL6947071

SCHEMBL6947071

C=CC(C)NC(=S)NNC(N)=S

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10907102 0.83
Methallibure SCHEMBL393014 0.82 GAA (0.31) GAA
Methallibure SCHEMBL4312430 0.80 GAA (0.30) GAA
SCHEMBL10816655 0.78 ALDH1A1 (0.35) ALDH1A1GAATSHR
SCHEMBL10815551 0.77
SCHEMBL10794899 0.76 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10GAA
SCHEMBL3799164 0.74
SCHEMBL21239911 0.73
Methallibure SCHEMBL6614118 0.71 ATM (0.45) ALDH1A1HPGDGAA
SCHEMBL23050405 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003106436-A1 NEMATICIDAL TETRAZOLE-CONTAINING TRIFLUOROBUTENES BAYER CROPSCIENCE AG (DE) 2003-12-24 WO disclosed