Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795425 | 0.91 | TDP1 (0.51) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL10799728 | 0.88 | POLB (0.52) | RAB9ALMNAPOLBMEN1KMT2A | |
| SCHEMBL10590200 | 0.85 | MEN1 (0.56) | RAB9ALMNAPOLBMEN1KMT2A | |
| SCHEMBL10885396 | 0.84 | MEN1 (0.55) | RAB9APOLBMEN1KMT2AMAPT | |
| SCHEMBL11026869 | 0.82 | MEN1 (0.53) | RAB9ALMNAPOLBMEN1KMT2A | |
| SCHEMBL11688572 | 0.82 | LMNA (0.60) | RAB9ALMNAPOLBMEN1KMT2A | |
| SCHEMBL10795979 | 0.81 | KMT2A (0.60) | RAB9APOLBMEN1KMT2AMAPT | |
| SCHEMBL7108246 | 0.81 | MEN1 (0.53) | RAB9ALMNAMEN1KMT2AMAPT | |
| SCHEMBL11685934 | 0.80 | LMNA (0.58) | RAB9ALMNAPOLBMEN1KMT2A | |
| SCHEMBL11077229 | 0.79 | LMNA (0.50) | RAB9ALMNAPOLBEPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |