Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077225 | 1.00 | LMNA (0.50) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11119140 | 0.91 | LMNA (0.47) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11119143 | 0.91 | LMNA (0.47) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11079132 | 0.90 | TLR8 (0.40) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11079135 | 0.90 | TLR8 (0.40) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11068163 | 0.90 | LMNA (0.50) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11068164 | 0.90 | LMNA (0.50) | LMNAPOLBRAB9AALDH1A1GAA | |
| SCHEMBL11071544 | 0.82 | ALDH1A1 (0.40) | LMNAPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11071541 | 0.82 | ALDH1A1 (0.40) | LMNAPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11079005 | 0.81 | TLR8 (0.41) | LMNAPOLBRAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |