Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Citrulline SCHEMBL28145515 | 0.95 | GSR (0.53) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL4101933 | 0.93 | GSR (0.62) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL4101937 | 0.93 | GSR (0.62) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL15909605 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL22426116 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL20587 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL9070200 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL4542892 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL215403 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| L-Citrulline SCHEMBL437142 | 0.91 | OTC (0.59) | GSRCYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687666-A | N-PARA-TOSYL-L-LYSINE CHLOROMETHYL KETONE | MINISTERIO DE SANIDAD Y ASISTENCIA SOCIAL INSTITUTO VENEZOLANO DE INVESTIGATIONES CIENTIFICAS (VE) | 1987-08-18 | — | — | US | disclosed |