L-Citrulline

L-Citrulline

SCHEMBL4101933

NC(=O)NCCCC(N)C(=O)O.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.62
CYP1A2 P05177 2/20 0.62
GRM8 O00222 1/20 0.62
GRM6 O15303 1/20 0.62
GRIN2D O15399 1/20 0.62
GRIN3B O60391 1/20 0.62
GRIK1 P39086 1/20 0.62
GRM5 P41594 1/20 0.62
GRIA1 P42261 1/20 0.62
GRIA2 P42262 1/20 0.62
GRIA3 P42263 1/20 0.62
SLC1A3 P43003 1/20 0.62
SLC1A2 P43004 1/20 0.62
SLC1A1 P43005 1/20 0.62
GRIA4 P48058 1/20 0.62
GRIN1 Q05586 1/20 0.62
GRIN2A Q12879 1/20 0.62
GRIK2 Q13002 1/20 0.62
GRIK3 Q13003 1/20 0.62
GRIN2B Q13224 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Citrulline SCHEMBL4101937 1.00 GSR (0.62) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL25232867 0.95 GSR (0.56) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL28145515 0.95 GSR (0.53) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL10796014 0.93 GSR (0.52) GSRCYP1A2GRM8GRM6GRIN2D
Arginine SCHEMBL6671119 0.92 GSR (0.53) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL15909604 0.91 OTC (0.59) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL437142 0.91 OTC (0.59) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL22426116 0.91 OTC (0.59) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL4542892 0.91 OTC (0.59) GSRCYP1A2GRM8GRM6GRIN2D
L-Citrulline SCHEMBL20587 0.91 OTC (0.59) GSRCYP1A2GRM8GRM6GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156563-A1 Glucan Compositions CIBA CORP. 2009-06-18 US disclosed
EP-1957168-A2 GLUCAN COMPOSITIONS Ciba Holding Inc. (CH) 2008-08-20 EP disclosed
WO-2007062995-A2 GLUCAN COMPOSITIONS CIBA HOLDING INC. (CH) 2007-06-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156563-A1 Glucan Compositions SORD, GLA, CUTA GSR 1276/4885CYP1A2 1619/4885GRM8 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.