Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889138 | 0.92 | LMNA (0.34) | LMNA | |
| SCHEMBL10356722 | 0.89 | LMNA (0.36) | LMNA | |
| SCHEMBL29050161 | 0.86 | LMNA (0.46) | LMNARARBMAOAMAOBALDH1A1 | |
| SCHEMBL11842143 | 0.83 | LMNA (0.42) | LMNARARBMAOAMAOBALDH1A1 | |
| SCHEMBL28001675 | 0.82 | LMNA (0.32) | LMNA | |
| SCHEMBL10902754 | 0.82 | LMNA (0.37) | LMNARARB | |
| SCHEMBL8668475 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL27995263 | 0.79 | LMNA (0.33) | LMNA | |
| SCHEMBL28905858 | 0.79 | LMNA (0.39) | LMNARARBMAOAMAOB | |
| SCHEMBL12746092 | 0.79 | DUT (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095855-B1 | PROCESS FOR POLYMERIZING ETHYLENE | UBE INDUSTRIES, LTD. (JP) | 1987-04-08 | — | — | EP | disclosed |
| US-4435550-A | GRIGNARD REAGENT, ALUMINUM HALIDE, ORGANOSILANE, TITANIUM HALIDE, ESTER, TRIALKYLALUMINUM | UBE INDUSTRIES, LTD. (JP) | 1984-03-06 | — | — | US | disclosed |
| US-4420594-A | USING AS CATALYST A REACTION PRODUCT OF AN ALUMINUM HALIDE WITH AN ORGANIC SILICON COMPOUND FOLLOWED BY REACTION WITH A GRIGNARD COMPOUND AND TITANIUM TETRAHALIDE | UBE INDUSTRIES, LTD. (JP) | 1983-12-13 | — | — | US | disclosed |
| EP-0095855-A1 | Process for polymerizing ethylene | UBE INDUSTRIES, LTD. (JP) | 1983-12-07 | — | — | EP | disclosed |
| EP-0074276-A1 | Process for polymerization of ethylene | UBE INDUSTRIES, LTD. (JP) | 1983-03-16 | — | — | EP | disclosed |
| EP-0074275-A1 | Process for polymerization of alpha-olefins | UBE INDUSTRIES, LTD. (JP) | 1983-03-16 | — | — | EP | disclosed |
| US-4365048-A | COORDINATION CATALYST, ALUMINUM COCATALYST, ESTER | UBE INDUSTRIES, LTD. (JP) | 1982-12-21 | — | — | US | disclosed |