Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477020 | 0.86 | THRB (0.48) | THRBTSHRALDH1A1 | |
| SCHEMBL3899513 | 0.86 | THRB (0.38) | THRBTSHRALDH1A1 | |
| SCHEMBL1645591 | 0.84 | THRB (0.44) | THRBTSHRALDH1A1 | |
| SCHEMBL11760936 | 0.83 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL19971229 | 0.79 | BBOX1 (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL9087691 | 0.77 | THRB (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL630863 | 0.77 | THRB (0.42) | THRBTSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL27971333 | 0.77 | THRB (0.41) | THRBTSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL7201069 | 0.75 | THRB (0.47) | THRBTSHRALDH1A1 | |
| SCHEMBL11404662 | 0.75 | ALDH1A1 (0.36) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4645663-A | Process for preparing a hair dye or hair bleach composition; a composition for use in this process; and the use of said composition to dye or bleach hair | SOCIETE ANONYME DITE: L'OREAL (FR) | 1987-02-24 | — | — | US | disclosed |
| US-4555246-A | Process for preparing a hair dye or hair bleach composition; a composition for use in this process; and the use of said composition to dye or bleach hair | L'OREAL (FR) | 1985-11-26 | — | — | US | disclosed |
| US-4438095-A | New cosmetic compositions for hair or skin conditioning, and the application thereof | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-03-20 | — | — | US | disclosed |